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Holger Kalthoff Selected Research

Pancreatic Ductal Carcinoma

5/2019The expression of death receptor systems TRAIL-R1/-R2/-R4, CD95 and TNF-R1 and their cognate ligands in pancreatic ductal adenocarcinoma.
9/2004Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays.
2/2004Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta.
1/2004Terminally modified oligodeoxynucleotides directed against p53 in an orthotopic xenograft model: a novel adjuvant treatment strategy for pancreatic ductal carcinoma.
12/2002Vascular endothelial growth factor mediated angiogenic potential of pancreatic ductal carcinomas enhanced by hypoxia: an in vitro and in vivo study.

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Holger Kalthoff Research Topics

Disease

81Neoplasms (Cancer)
01/2022 - 01/2002
36Pancreatic Neoplasms (Pancreatic Cancer)
01/2022 - 09/2002
26Neoplasm Metastasis (Metastasis)
06/2021 - 11/2003
24Adenocarcinoma
06/2021 - 09/2002
7Colorectal Neoplasms (Colorectal Cancer)
05/2020 - 01/2002
7Carcinoma (Carcinomatosis)
01/2016 - 12/2003
6Inflammation (Inflammations)
10/2021 - 11/2005
5Pancreatic Ductal Carcinoma
05/2019 - 12/2002
4Lung Neoplasms (Lung Cancer)
01/2014 - 03/2002
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2014 - 10/2002
3Carcinogenesis
08/2018 - 05/2007
3Circulating Neoplastic Cells
06/2018 - 05/2015
3Lymphatic Metastasis
01/2018 - 03/2004
3Chronic Pancreatitis
01/2018 - 11/2005
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2016 - 03/2002
3Necrosis
04/2015 - 12/2002
3Fibrosis (Cirrhosis)
03/2012 - 09/2002
2Penile Neoplasms (Penile Cancer)
01/2021 - 01/2018
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
05/2020 - 11/2016
2Hypoxia (Hypoxemia)
08/2014 - 12/2002
2Disease Progression
01/2014 - 03/2004
1Autoimmune Diseases (Autoimmune Disease)
06/2017
1Leprosy (Hansen's Disease)
06/2017
1Mouth Neoplasms (Oral Cancer)
01/2016

Drug/Important Bio-Agent (IBA)

16Proteins (Proteins, Gene)FDA Link
05/2020 - 03/2002
8GemcitabineFDA Link
10/2021 - 04/2003
8Biomarkers (Surrogate Marker)IBA
10/2021 - 06/2015
7LigandsIBA
05/2019 - 04/2008
6Death Domain ReceptorsIBA
05/2019 - 04/2005
6Pharmaceutical PreparationsIBA
06/2017 - 04/2003
6CytokinesIBA
12/2015 - 11/2005
6Messenger RNA (mRNA)IBA
05/2015 - 09/2002
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2018 - 03/2008
5Interleukin-8 (Interleukin 8)IBA
02/2013 - 09/2007
5NF-kappa B (NF-kB)IBA
07/2010 - 04/2003
4Keratin-20 (Cytokeratin 20)IBA
06/2018 - 10/2005
4Interleukin-6 (Interleukin 6)IBA
12/2015 - 09/2007
3AntigensIBA
10/2021 - 01/2004
3TNF-Related Apoptosis-Inducing LigandIBA
06/2021 - 04/2008
3MicroRNAs (MicroRNA)IBA
11/2016 - 01/2014
3RNA (Ribonucleic Acid)IBA
11/2016 - 03/2004
3IntegrinsIBA
10/2015 - 12/2013
3Phosphotransferases (Kinase)IBA
02/2014 - 12/2003
3Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
02/2013 - 01/2002
3Biological ProductsIBA
12/2011 - 05/2003
3CaspasesIBA
10/2009 - 04/2008
3Transforming Growth Factor beta (TGF-beta)IBA
04/2007 - 09/2002
3DNA (Deoxyribonucleic Acid)IBA
09/2004 - 03/2004
2Liposomes (Liposome)IBA
01/2022 - 04/2021
2AntibodiesIBA
05/2019 - 07/2010
2DisintegrinsIBA
08/2018 - 10/2013
2Metalloproteases (Metalloproteinases)IBA
08/2018 - 10/2013
2Ion Channels (Ion Channel)IBA
10/2017 - 01/2017
2Cell Adhesion MoleculesIBA
12/2015 - 12/2003
2ChemokinesIBA
04/2015 - 06/2012
2TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
02/2014 - 02/2013
2Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA
01/2014 - 01/2012
2EnzymesIBA
10/2013 - 08/2008
2TNF Receptor-Associated Factor 2 (TRAF2)IBA
02/2013 - 04/2005
2Indicators and Reagents (Reagents)IBA
02/2013 - 03/2004
2Tyrosine Kinase InhibitorsIBA
01/2013 - 09/2010
2Sunitinib (Sutent)FDA Link
01/2013 - 09/2010
2Chemokine ReceptorsIBA
06/2012 - 12/2011
2Infliximab (Remicade)FDA Link
06/2011 - 03/2008
2Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
02/2011 - 08/2008
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2010 - 12/2002
2Thymidine KinaseIBA
03/2004 - 03/2002
2Ganciclovir (Cytovene)FDA LinkGeneric
03/2004 - 03/2002
2Plasminogen InactivatorsIBA
11/2003 - 01/2002
2Plasminogen Activator Inhibitor 1IBA
11/2003 - 01/2002
1IronIBA
01/2022
1Immunoglobulin Fab FragmentsIBA
01/2022
1Fas Ligand Protein (Fas Ligand)IBA
10/2021
1SphingomyelinsIBA
04/2021
1AcidsIBA
04/2021
1Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA
04/2021
1Oncogene Proteins (Oncogene Protein)IBA
01/2021
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
05/2019
1ThrombospondinsIBA
08/2018
1navitoclaxIBA
01/2018
1CyclinsIBA
01/2018
1APG350IBA
01/2018
1Potassium Channels (Potassium Channel)IBA
10/2017
1Clofazimine (Lamprene)FDA Link
06/2017
1CarcinogensIBA
11/2016
1Transforming Growth Factors (Transforming Growth Factor)IBA
11/2016
1Diclofenac (SR 38)FDA LinkGeneric
01/2016
1MTOR InhibitorsIBA
01/2016
1Mycophenolic Acid (Cellcept)FDA LinkGeneric
01/2016
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
01/2016
1A 7 (A-7)IBA
01/2016
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
01/2016

Therapy/Procedure

21Therapeutics
10/2021 - 03/2002
9Drug Therapy (Chemotherapy)
01/2018 - 04/2003
8Heterologous Transplantation (Xenotransplantation)
01/2018 - 10/2002
3Palliative Care (Palliative Therapy)
01/2018 - 10/2005
3Pancreatectomy
03/2008 - 01/2006
2Neoadjuvant Therapy
12/2015 - 08/2007
1Precision Medicine
05/2020
1Combination Drug Therapy (Combination Chemotherapy)
01/2016